Upon completion of my Master’s Degree in Microelectronics at University of Bordeaux in 2008, I wanted to conduct further research in an academic laboratory setting. I commenced a Ph.D. program developing design, modeling and control strategies of mechatronics nanotweezers in order to enhance detection of bio-chemical reactions on DNA molecules.

Thereafter, I continued as project researcher/consultant to develop several research projects in microtechnologies for the University of Tokyo, Stanley Electric Co. Ltd., Santec Corporation, designing new microsystems for telecommunications and medical applications.

Since 2018, I joined the managing of the European-funded projet HoliFAB for Fluigent, which aims at generalizing microfluidic (or lab-on-chip) technologies for next generation bio-chemical instruments. We drive a consortium of 10 partners for chip production by 3D printing or injection molding and for optimized instruments production.

Besides 10 years of experiences in microtechnologes, biotechnologies and innovative R&D projects, I think to have strong knowledge of academic, industrial and international partners, and have acquired solid routines for analyze, optimize and automate processes. In order to move even further, my recent personal interests are to embrace machine learning and data science methods.

2018 - 2019 : University course, degree in Artificial Intelligence and Machine Learning >>>

in Sorbonne university (France)

2008 - 2012 : PhD, doctor in Microsystems and Control theory, with distinction

in LIMMS (CNRS/IIS University of Tokyo joint laboratory)(Japan) and FEMTO-ST institute (France)

2007 - 2008 : Master, with specialization in microelectronics, with distinction

Bordeaux Graduate School of Engineering ENSEIRB/University of Bordeaux (France)

2006 - 2007 : Sabbatical year, voluntary works in South America

in NGO Intillapu (Solar cookers development in Chile), WWOOF Finca El Peregrino (Organic farming in Argentina) and NGO Los Gorriones (Orphanage in Peru)

2001 - 2006 : Bachelor to master, in electrical engineering, with distinctions

University of Bordeaux, then Bordeaux Graduate School of Engineering ENSEIRB (France)

2018 - 2020: H2020 European HoliFAB project manager, at Fluigent

Coordination of HoliFAB for the industrialisation of Microfluidics

- Management of a consortium of 10 academic and industrial partners
- Reporting technical and financial progress to the European Commission
- Setting project communication and marketing strategies
- Adaptation of the Fluigent custom instrument design pilot line
- Development of a new CAD tool for microfluidic project in C# and Python
- Development of new hardware microfluidic integration, i.e. standardization of building blocks, connectors, designs and assemblies

2014 - 2017: Project researcher, at the University of Tokyo (Pr. Toshiyoshi laboratory)

and SANTEC Corp.

Optical MEMS scanners for tunable laser sources & medical OCT

We developed a new tunable laser source based on MEMS and VCSEL technologies for OCT imaging. Thanks to this new and better source of light, the imaging by OCT was improved and help better diagnostic of irregularities inside eyes, skins and inside-body tissues.
Keywords: OCT, medical imaging, MEMS, silicon microsystems, MEMS mirror, mechanical design, layout, simulation, microfabrication, standard clean-room process, modeling, COMSOL Multiphysics, Python, LabVIEW, instrumentation, system integration
Details (link soon available) & Santec laser tunable sources & Santec SS-OCT

2012 - 2014 : Post-doctoral fellow, at the University of Tokyo (Pr. Toshiyoshi laboratory)

and Stanley Electric Co.

Digitally programmable resonators by PZT-SOI process

With the collaboration of Stanley Electric Co, we were developed PZT-MEMS oscillators array with more than 30 resonance modes that could be selectively excited by choosing an appropriate set of drive and pick-up electrodes distributed on the array network. This device can be used in RF systems in order to address several communications frequencies or bandwidths.
Keywords: MEMS, silicon microsystems, piezo-electricity, PZT, mechanical design, layout, simulation, modeling, COMSOL Multiphysics, Python, LabVIEW, instrumentation, Radio-Frequency circuit
>>> (link soon available)

2008 - 2012 : PhD student, at the University of Tokyo (LIMMS & Pr. Fujita laboratory)

and FEMTO-ST (Microsystems control)

Control of silicon nano-tweezers for DNA molecules characterization

To move towards systematic biological or medical analysis on DNA strands, microsystems (MEMS) are appropriate tools as they can integrate accurate molecular level engineering tools and can be cheaply produced with highly parallel process. With MEMS tweezers, DNA molecules were mechanically characterized in order to understand their biological and chemical properties.
Keywords: MEMS, silicon microsystems, mechanical design, layout, simulation, modeling, control theory, state feedback, COMSOL Multiphysics, Matlab, dSPACE, LabVIEW, instrumentation, experiments automatization, microfluidics, bio-experiments, DNA, biological cells
More details & PhD thesis

2008 : Intern student 7 months, at STMicroelectronics (Crolles/Grenoble, France)

Design of an RF Antena Switch in SOI technology

Contents is ST Microelectronics confidential
Keywords: Radio-Frequency, Integrated Circuits, microelectronics design, simulation, layout, Cadence, CMOS 130 nm SOI technology

2007 : Intern student 3 months, at University of Kumamoto (Pr. Inoue laboratory, retired)

Design of a CMOS Low-Power Low-Frequency Oscillator

In the framework of the PhD of Felix Timischl, the design of a CMOS low-power low-frequency oscillator has been proposed for an ultrasonic distance measurement system. A current source charges a low capacitance, and a voltage level control circuit control the charge or the discharge of the capacitance. A current control circuit is also designed to ensure a supply and temperature independency.
Keywords: Integrated Circuits, microelectronics design, simulation, HSPICE, 0.35 μm 2-poly 4-metal CMOS technology
Internship report

Languages

English (fluent, TOEFL: 563/650 in 2006)

French (native)

Spanish (native)

Japanese (daily communication, N3 level obtained in 2015, in preparation of N2)

Electronics

Integrated Circuit design, simulation (with Mentor, Cadence, Ansoft, VHDL-AMS, Spice) and instrumentation

Experimental instrumentation with LabVIEW

Multiphysics

Simulation with COMSOL (mechanics, electrostatic and fluidics)

Modeling with MATLAB and Python (dynamical systems and control theory)

Microfabrication

Standard cleanroom processes for MEMS and Microfluidics

Design & Layout

L-Edit, Cle-Win, MathCAD, Solidworks (3D), Blender (3D & animation)

Programming

C, C++, VHDL-AMS, Spice, SystemC, HLS, Matlab, Java

Basic web development (HTML, CSS, PHP)

Hobbies

Sports (especially Football, Tennis, Windsurfing)

Discovering lifes and cultures abroad (especially Latin cultures)

Dance on Latin musics (especially Salsa) and Cooking

• "Elucidating the mechanism of the considerable mechanical stiffening of DNA induced by the couple Zn2+/Calix[4]arene-1,3-O-diphosphorous acid"
  Y. Tauran, M.C. Tarhan, L. Mollet, J.-B. Gerves, M. Kumemura, L. Jalabert, N. Lafitte, I. Byun, B. Kim, H. Fujita, D. Collard, F. Perret, M. Desbrosses, D. Leonard, C. Goutaudier, and A.W. Coleman, Scientific Reports, vol.8, 1226 (2018) [.pdf]
• "Real-time mechanical characterization of DNA degradation under therapeutic x-ray and its theoretical modelling"
  G. Perret, T. Lacornerie, F. Manca, S. Giordano, M. Kumemura, N. Lafitte, L. Jalabert, M.C. Tarhan, E. Lartigau, F. Cleri, H. Fujita, and D. Collard, Microsystems & Nanoengineering, vol.2, 16062 (2016) [.pdf]
• "A rapid and practical technique for real-time monitoring of biomolecular interactions using mechanical responses of macromolecules"
  M.C. Tarhan, N. Lafitte, Y. Tauran, L. Jalabert, M. Kumemura, G. Perret, B.J. Kim, A.W. Coleman, H. Fujita, and D. Collard, Scientific Reports, vol.6, 28001 (2016) [.pdf]
• "Direct electrical and mechanical characterization of in situ generated DNA between the tips of silicon nanotweezers (SNT)"
  S.L. Karsten, M. Kumemura, L. Jalabert, N. Lafitte, L.C. Kudo, D. Collard, and H. Fujita, Lab on a Chip, vol.16, pp.2099–2107 (2016) [.pdf]
• "Improvement of Silicon Nanotweezers Sensitivity for Mechanical Characterization of Biomolecules Using Closed-Loop Control"
  N. Lafitte, Y. Haddab, Y. Le Gorrec, H. Guillou, M. Kumemura, L. Jalabert, D. Collard, and H. Fujita, IEEE/ASME Trans Mechatron, vol.20 (3) pp.1418-1427 (2015) [.pdf]

• especially in IEEE MEMS (3), MicroTAS (8), Transducers (5) and IROS (1)
• 8 in domestic conferences

• Encyclopedia of Nanotechnology (Springer)(2011 & 2015)
• Micro and Nano Manipulation (Wiley-VCH)(2015)

• 4 article reviews for IEEE/ASME Trans. Mech, IEEE JMEMS and Adv. Robotic
• 1 project review for National Heatlh Institutes (US) start-up founding program

Dr. Keiji ISAMOTO (Santec Corp., Nagoya), kisamoto[at]santec-net.co.jp

Pr. Hiroshi TOSHIYOSHI (IIS-University of Tokyo, Tokyo), hiro[at]iis.u-tokyo.ac.jp

Pr. Dominique COLLARD (LIMMS/CNRS-IIS, Tokyo), collard[at]iis.u-tokyo.ac.jp

Pr. Hiroyuki FUJITA (IIS-University of Tokyo, Tokyo), hfujita[at]iis.u-tokyo.ac.jp

Pr. Yann LE GORREC (FEMTO-ST, Besançon), yann.le.gorrec[at]ens2m.fr

Pr. Yassine HADDAB (FEMTO-ST, Besançon), yassine.haddab[at]ens2m.fr

Dr. Andreia CATHELIN (STMicroelectronics, Crolles), andreia.cathelin[at]st.com

Pr. Yann DEVAL (IMS-ENSEIRB, Bordeaux), yann.deval[at]ims-bordeaux.fr